Prevotella copri and its related taxa are widely detected in mammalian gut microbiomes and have been linked with an enterotype Collectable Coins in humans.However, their microevolution and macroevolution among hosts are poorly characterized.In this study, extensively collected marker genes and genomes were analyzed to trace their evolutionary histo
Trop-2 is a transmembrane signal transducer that can induce cancer growth.Using antibody targeting Tea Strainer and N-terminal Edman degradation, we show here that Trop-2 undergoes cleavage in the first thyroglobulin domain loop of its extracellular region, between residues R87 and T88.Molecular modeling indicated that this cleavage induces a profo
Trop-2 is a transmembrane signal transducer that can induce cancer growth.Using antibody targeting Tea Strainer and N-terminal Edman degradation, we show here that Trop-2 undergoes cleavage in the first thyroglobulin domain loop of its extracellular region, between residues R87 and T88.Molecular modeling indicated that this cleavage induces a profo
Transporters are dynamic membrane proteins that are essential to the physiology of cells.To function, transporters must cycle between various conformational states, so to understand their mechanistic details, it is critical to characterize how their structure changes during the transport cycle.One approach to studying the dynamics of transporters t
BackgroundPhysical activity promotes health and longevity.Further elaboration of the role of physical activity for human health in epidemiological studies on large samples requires accurate methods that are easy to use, cheap, and possible to repeat.The use of telecommunication technologies such as cell phones is highly interesting in this respect.